Hi Jose! Welcome to Rochester! I also work at the Guggenheim. I rent a studio apartment, not too far from Downtown (but too far for me to go walking) and it's way more expensive than that, so I believe those are good values. Mayo offers a lot of shuttle buses, but there are not many offered but the city itself, so check if there is shuttle coming from these buildings. My building (The Park, at the Kutzky park) offers free shuttle, that leaves us by walking distance from the Guggenheim and other Mayo buildings.
Some people use bike, but consider that the winter is tough and it's hard to bike in snowing days!